Diabetes Research and Clinical Practice - Volume 106 - Supplement 1 - November 2014 - page 9

S2
Oral presentation abstracts / Diabetes Research and Clinical Practice 106S1 (2014) S1–S41
relative terms (41% of daily energy intake; DEI). Carbohydrate
ingestion was rather low both in absolute (150±15g) and
relative terms (39% of DEI), however 20% of the carbohydrates
were consumed as sucrose (30g). Protein intake (73±5g/19%
of DEI) was rather low and fiber consumption (15±2g)
definitely too low. In three subjects. complete CGM-datasets
before and after nutrition training have yet been compiled:
Target adherence reduced glucose variability (STD) from
35 to 25mg/dl; time spent in hypoglycemia (IG
<
70mg/dl)
decreased from 15% to 9% of the day, respectively; time spent
in hyperglycemia (IG
>
80mg/dl) decreased from 5% to 2% of
the day.
Conclusion:
Inadequate postbariatric eating behavior is
prevalent in symptomatic NIPHS subjects. In contrast
to previously published bariatric literature, sucrose and
fat consumption are exceeding and fiber and complex
carbohydrates falling short of prescribed and desirable
amounts. SANT
focusing on strict adherence to adequate nutrition
targets
dramatically reduced prandial glucose peaks, overall
glucose variability and time spent
<
70mg/dl in three
preliminary cases. We challenge the notion of RYGB-induced
prudent food preference. SANT helps to avoid sweetened food
as far as possible in order to balance accelerated glucose
appearance after RYGB.
Reference(s)
[1] Bueter M et al. (2011) Alterations of sucrose preference after
Roux-en-Y gastric bypass.
Physiol Behav. 24;104(5): 709
21.
[2] Camastra et al. (2013) Long-term effects of bariatric surgery
on meal disposal and beta-cell function in diabetic and
nondiabetic patients.
Diabetes; 62: 3709
17.
[3] Saeidi N et al. (2013) Reprogramming of intestinal glucose
metabolism and glycemic control in rats after gastric bypass.
Science; 341: 406–410.
[4] Rett K et al. (2013) Continuous glucose monitoring (CGM)
discloses high glycaemic variability in patients with “late
dumping” after RYGB.
Diabetologia 56 [Suppl. 1] S 273.
OP3
BIDIRECTIONAL ASSOCIATIONS BETWEEN DEPRESSION
AND TYPE 2 DIABETES IN ADULTS: RESULT FROM QINGDAO
DIABETES PREVENTION PROGRAM
F. Ning
1
, Y.M. Wang
2
, S.J. Wang
1
, H.R. Nan
3
, J.P. Sun
4
,
D. Zhang
5
, L. Zhang
6
, W.G. Gao
7
, Z.C. Pang
1
, Q. Qiao
8
.
1
Qingdao
Centers for Disease Control and Prevention, Qingdao,
2
Dongying
People’s Hospital, Dongying, China;
3
HongKong University of
Science and Technology, HongKong, Hong Kong,
4
Qingdao Center
for Disease Control and Prevention,
5
Huangdao Centers for Disease
Control and Prevention,
6
Qingdao Endorcinology and Diabetes
Hospital, Qingdao,
7
AstraZeneca Pharmaceutical Company,
Shanghai, Shanghai, China;
8
University of Helsinki, Helsinki,
Finland
Background:
The bidirectional association between diabetes
and depression in clinical patients were widely evidenced.
However, the association between two disorders in adults
from the community was not well known. We will investigate
the bidirectional associations between depression syndrome
and type 2 diabetes in adults of Chinese community settings.
Method:
Two population-based cross-sectional studies on
diabetes were performed in 4598 men and 7026 women
aged 35–74 years in 2006 and 2009. The 2006 World Health
Organization/International Diabetes Federation diagnostic
criteria and Zung self-assessment score were employed
to identify type 2 diabetes and depression syndrome,
respectively. Multivariate Logistic regression was employed
to assess their associations between depression and type 2
diabetes, adjusting for age, sex, body mass index, residential
area, serum triglycerides, hypertension, family history of
diabetes, marital status, education level, income level,
occupational status, current smoking and current drinking.
Result:
A total of 7421, 38.9% male, 51 (10.4) years, was
included in the current study, with prevalence of type 2
diabetes and depression 16.1% and 11.3%, respectively. Age,
sex, residential area, body mass index, serum cholesterol,
hypertension and family history of diabetes are significantly
associated with either type 2 diabetes or depression
prevalence in a univariate model. The significant odd ratios
of depression for type 2 diabetes were 1.31 (1.08–1.60), and
1.30 (1.07–1.59) of type 2 diabetes for depression in two
separated multivariate models with adjustment of other
conventional factors. Depression was significantly associated
with newly diagnosed diabetes, but moderate effect on
previous diagnosed diabetes in a sensitive analysis, with odd
ratios of 1.28 (1.02–1.60) and 1.23 (0.91–1.67), respectively.
Systolic or diastolic blood pressure instead of hypertension,
waist circumference instead of body mass index fitted in a
multivariate model did not change the trends substantially.
Conclusion:
To our knowledge, this is first time to indicate
that depression is an independent risk factor for type 2
diabetes and their bidirectional association in Chinese adults.
Early identification and lifestyle intervention may prevent
residents from risk of diabetes and type 2 diabetes. The causal
relationship between depression and diabetes warranted
further investigation.
Funded by the World Diabetes Foundation (WDF05–108&07–
308)
Reference(s)
[1] Mezuk B, Eaton WW, Albrecht S, et al. Depression and type 2
diabetes over the lifespan: a meta-analysis. Diabetes Care
,
2008, 31: 2383–2390.
[2] Knol MJ, Twisk JW, Beekman AT, et al. Depression as a risk
factor for the onset of type 2 diabetes mellitus. A meta-
analysis. Diabetologia, 2006, 49: 837–45.
[3] Pan A, Lucas M, Sun Q, et al. Bidirectional association between
depression and type 2 diabetes mellitus in women. Arch Intern
Med, 2010, 22; 170: 1884–91.
[4] Look AHEAD Research Group. Impact of Intensive Lifestyle
Intervention on Depression and Health-Related Quality of Life
in Type 2 Diabetes: The Look AHEAD Trial. Diabetes Care, 2014,
37: 1544–53.
OP4
EFFICACY OF MOBILE DIABETES CARE BASED ON A NEWLY
DEVELOPED PATIENT DECISION SUPPORT SYSTEM (PDSS)
E.K. Kim
1
, S.H. Kwak
1
, K.S. Park
1
, H.C. Jang
1
, Y.M. Cho
1
.
1
Internal Medicine, Seoul National University College of Medicine,
Seoul, Korea, Republic of
Background:
There have been many efforts to develop
electronic devices managing one’s health, especially chronic
metabolic disorders which need continuous lifestyle mod-
ification. Several u-healthcare and m-healthcare system
were introduced, but most of their functions are not much
interactive and just limited to show individual data. We aimed
to evaluate efficacy and user’s satisfaction of newly invented
mobile healthcare system, which named ‘Patient Decision
Support System (PDSS)’.
Method:
This was a pilot study to examine the efficacy of a
new mobile diabetes care system. The PDSS was designed to
help patients with managing their glucose levels, improving
dietary habits including intake of calorie, and keeping exercise
easily and steadily. It consists of android-based smartphone
application, Bluetooth glucometer and activity tracker, and
website for the medical team to monitor input data of each
subject. The patients aged between 20 and 80 years with
type 2 diabetes mellitus and HbA1c of 6.5% or higher were
recruited from December 2013 to January 2014. Participants
were informed to measure blood glucose level with supplied
glucometer at least once a day, to input whatever they eat,
and to carry the activity tracker on themselves. The change
in HbA1c after 12 weeks of use PDSS was analyzed as well
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